22 Results for "

Crotalaria pallida Ait.

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Crotalaria pallida Ait." in MCE Product Catalog:

44
Apilimod
Apilimod
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44 Publications Verification
Art. -Nr.: HY-14644
CAS. Nr.: 541550-19-0
Reinheit:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Target:  

Interleukin Related PIKfyve

Forschungsgebiete:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
44
Apilimod mesylate
Apilimod mesylate
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44 Publications Verification
Art. -Nr.: HY-14644A
CAS. Nr.: 870087-36-8
Reinheit:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Target:  

Interleukin Related PIKfyve

Forschungsgebiete:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
2
2′-Hydroxygenistein
2′-Hydroxygenistein
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2 Cited Publications
Art. -Nr.: HY-N1735
CAS. Nr.: 1156-78-1
Category:  

Flavonoids Leguminosae Plants Crotalaria pallida Ait. Isoflavones

Target:  

β-glucuronidase Bacterial

2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively .
(S)-Campesterol
(S)-Campesterol
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Art. -Nr.: HY-N1459A
CAS. Nr.: 4651-51-8
Synonyms: 5-Ergosten-3β-ol
Category:  

Bursera simaruba (L.) Sarg. Plants Burseraceae Steroids

Target:  

Drug Isomer

(S)-Campesterol (5-Ergosten-3β-ol) is a phytosterol (terpenoid) found in the leaves of Plumeria rubra L., form acutifolia (Ait) Woodson .
Usaramine N-oxide
Usaramine N-oxide
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Art. -Nr.: HY-N6827
CAS. Nr.: 117020-54-9
Category:  

Alkaloids Pyrrole Alkaloids Leguminosae Plants Crotalaria pallida Ait. Disease Research Fields Inflammation/Immunology

Target:  

Others

Usaramine N-oxide, a alkaloid isolated from Crotalaria pallida, possesses anti-inflammatory activities .
Usaramine
Usaramine
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Art. -Nr.: HY-N6931
CAS. Nr.: 15503-87-4
Category:  

Infection Alkaloids Pyrrole Alkaloids Leguminosae Plants Crotalaria pallida Ait. Disease Research Fields

Target:  

Bacterial

Usaramine is a pyrrolizidine alkaloid that can be isolated from seeds of Crolatalaria pallida. Usaramine selective Usaramine demonstrates antibiofilm activity against Staphylococcus epidermidis. Usaramine can be used for the research of bacterial infections .
Eurycarpin A
Eurycarpin A
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Art. -Nr.: HY-N3882
CAS. Nr.: 166547-20-2
Category:  

Flavonoids Plants Crotalaria ferruginea Grah. ex Benth. Fabaceae Isoflavones

Target:  

Others

Eurycarpin A is isoflavonoid analog isolated from the ethanol extract of the Chinese folk medicine Crotalaria ferruginea .
Apilimod hydrochloride
Apilimod hydrochloride
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Art. -Nr.: HY-14644B
CAS. Nr.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Target:  

NOD-like Receptor (NLR)

Forschungsgebiete:  

Infection Inflammation/Immunology

Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
Leteprinim potassium
Leteprinim potassium
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Art. -Nr.: HY-120251A
CAS. Nr.: 192564-13-9
Reinheit:  ≥99.0%
Synonyms: AIT-082
Target:  

Reactive Oxygen Species (ROS)

Forschungsgebiete:  

Neurological Disease

Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
Leteprinim
Leteprinim
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Art. -Nr.: HY-120251
CAS. Nr.: 138117-50-7
Synonyms: AIT-082 free acid
Target:  

Reactive Oxygen Species (ROS)

Forschungsgebiete:  

Neurological Disease

Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
Usaramine N-oxide (Standard)
Usaramine N-oxide (Standard)
0 Images
Art. -Nr.: HY-N6827R
CAS. Nr.: 117020-54-9
Category:  

Alkaloids Pyrrole Alkaloids Leguminosae Plants Crotalaria pallida Ait.

Target:  

Reference Standards Others

Usaramine N-oxide (Standard) is the analytical standard of Usaramine N-oxide. This product is intended for research and analytical applications. Usaramine N-oxide, a alkaloid isolated from Crotalaria pallida, possesses anti-inflammatory activities .
Barbacarpan
Barbacarpan
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Art. -Nr.: HY-N2915
CAS. Nr.: 213912-46-0
Category:  

Flavonoids Leguminosae Plants Crotalaria pallida Ait.

Target:  

Others

Barbacarpan is a Flavonoids product that can be isolated from the herbs of Crotalaria barbata .
Nilgirine
Nilgirine
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Art. -Nr.: HY-N8663
CAS. Nr.: 21009-05-2
Category:  

Alkaloids Leguminosae Plants Crotalaria pallida Ait.

Target:  

Others

Nilgirine is a Alkaloids product that can be isolated from the herbs of Crotalaria mucronata .
Intermedine N-oxide
Intermedine N-oxide
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Art. -Nr.: HY-W707957
CAS. Nr.: 95462-14-9
Category:  

Pyrrolizidine Alkaloids Alkaloids Animals

Target:  

Drug Intermediate

Intermedine N-oxide is a pyrrolizidine alkaloid indicine that can be found in Crotalaria spectabilis. Intermedine N-oxide shows anticancer activity .
Fulvine
Fulvine
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Art. -Nr.: HY-133589
CAS. Nr.: 6029-87-4
Target:  

Drug Derivative

Forschungsgebiete:  

Cardiovascular Disease Metabolic Disease

Fulvine is a pyrrolizidine alkaloid isolated from the seeds of Crotalaria fulva. Fulvine is hepatotoxic and can be used to induce hypertensive pulmonary vascular disease in vivo .
6'-O-Cinnamoyl-8-epikingisidic acid
6'-O-Cinnamoyl-8-epikingisidic acid
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Art. -Nr.: HY-N2721
CAS. Nr.: 1403984-03-1
Synonyms: 6'-O-trans-cinnamoyl 8-epikingisidic acid
Category:  

Oleaceae Ligustrum lucidum Ait. Simple Phenylpropanols Other Diseases Phenylpropanoids Plants Disease Research Fields

Target:  

Others

6'-O-Cinnamoyl-8-epikingisidic acid (6'-O-trans-cinnamoyl 8-epikingisidic acid) is a secoiridoid constituent isolated from the dried fruits of Ligustrum lucidum AIT .
Kushenol L
Kushenol L
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Art. -Nr.: HY-N3414
CAS. Nr.: 101236-50-4
Category:  

Flavanonols Flavonoids Leguminosae Metabolic Disease Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields

Target:  

Others

Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects .
Trichodesmine N-oxide
Trichodesmine N-oxide
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Art. -Nr.: HY-N16484
CAS. Nr.: 55727-46-3
Category:  

Alkaloids Other Alkaloids Plants Trichodesma incanum (Bunge) A.DC. Boraginaceae

Target:  

Others

Trichodesmine N-oxide is the oxidized form of a pyrrolizidine alkaloid (PA) that can be isolated from the sunn hemp (Crotalaria juncea) teas. PAs are secondary metabolites in plants, which may exhibit toxicity and carcinogenicity .
Usaramine (Standard)
Usaramine (Standard)
0 Images
Art. -Nr.: HY-N6931R
CAS. Nr.: 15503-87-4
Category:  

Alkaloids Pyrrole Alkaloids Leguminosae Plants Crotalaria pallida Ait.

Target:  

Reference Standards Bacterial

Usaramine (Standard) is the analytical standard of Usaramine. This product is intended for research and analytical applications. Usaramine is a pyrrolizidine alkaloid isolated from seeds of Crolatalaria pallida. Usaramine demonstrates a highlighted antibiofilm activity against Staphylococcus epidermidis by reducing more than 50% of biofilm formation without killing the bacteria .
Neodidymelliosides A
Neodidymelliosides A
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Art. -Nr.: HY-N12606
Category:  

Microorganisms Saccharides Monosaccharides

Target:  

Fungal

Neodidymelliosides A (compound 1)It is a secondary metabolite of fungi and has a significant inhibitory effect on Staphylococcus aureus and Candida albicans biofilms. Neodidymelliosides AIt also has anti-cancer activity and can inhibit KB3.1 (cervix),PC-3 (prostate),MCF-7(breast),SKOV-3 (ovary),A431 (skin )and A549 (lung )Cell viability of cell lines .
Assay Types