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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
Crotalaria pallida Ait.
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "Crotalaria pallida Ait." in MCE Product Catalog:
44
44 Publications Verification
Synonyms: STA 5326; LAM-002A free base; AIT-101
Target:
Áreas de investigación:
Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
44
44 Publications Verification
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Target:
Áreas de investigación:
Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
2
Target:
Category:
Target:
Referencia número: HY-N6827
No. CAS: 117020-54-9
Category:
Alkaloids Pyrrole Alkaloids Leguminosae Plants Crotalaria pallida Ait. Disease Research Fields Inflammation/Immunology
Target:
Referencia número: HY-N6931
No. CAS: 15503-87-4
Category:
Infection Alkaloids Pyrrole Alkaloids Leguminosae Plants Crotalaria pallida Ait. Disease Research Fields
Target:
Referencia número: HY-N3882
No. CAS: 166547-20-2
Target:
Referencia número: HY-14644B
No. CAS: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Target:
Áreas de investigación:
Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
Synonyms: AIT-082
Target:
Áreas de investigación:
Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
Referencia número: HY-120251
No. CAS: 138117-50-7
Synonyms: AIT-082 free acid
Target:
Áreas de investigación:
Leteprinim (AIT-082 free acid), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim is a hypoxanthine derivative neurotrophic agent. Leteprinim can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species .
Referencia número: HY-N6827R
No. CAS: 117020-54-9
Target:
Referencia número: HY-N2915
No. CAS: 213912-46-0
Category:
Target:
Referencia número: HY-N8663
No. CAS: 21009-05-2
Category:
Target:
Referencia número: HY-W707957
No. CAS: 95462-14-9
Category:
Target:
Target:
Áreas de investigación:
Fulvine is a pyrrolizidine alkaloid isolated from the seeds of Crotalaria fulva. Fulvine is hepatotoxic and can be used to induce hypertensive pulmonary vascular disease in vivo .
Referencia número: HY-N2721
No. CAS: 1403984-03-1
Synonyms: 6'-O-trans-cinnamoyl 8-epikingisidic acid
Category:
Oleaceae Ligustrum lucidum Ait. Simple Phenylpropanols Other Diseases Phenylpropanoids Plants Disease Research Fields
Target:
Referencia número: HY-N3414
No. CAS: 101236-50-4
Category:
Flavanonols Flavonoids Leguminosae Metabolic Disease Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields
Target:
Referencia número: HY-N16484
No. CAS: 55727-46-3
Target:
Referencia número: HY-N6931R
No. CAS: 15503-87-4
Target:
Referencia número: HY-N12606
Category:
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
